In response to two clinical studies observing an increased risk of lung cancer in heavy smokers taking long-term high doses (5 to10 times the recommended dose) of beta-carotene (see Safety) the German food industry introduced voluntarily a self-restriction for beverages (max. View abstract. 2007;137(9):2098-2105. Drug-nutrient interaction. Virtamo J, Pietinen P, Huttunen JK, et al. Galli, F., Battistoni, A., Gambari, R., Pompella, A., Bragonzi, A., Pilolli, F., Iuliano, L., Piroddi, M., Dechecchi, M. C., and Cabrini, G. Oxidative stress and antioxidant therapy in cystic fibrosis. Zhang, X., Dai, B., Zhang, B., and Wang, Z. Vitamin A and risk of cervical cancer: a meta-analysis. Beta-carotene and other carotenoids as antioxidants. View abstract. View abstract. Cancer Causes Control 2010;21(11):1745-1757. Mathews-Roth, M. M., Pathak, U. That being said, if you don't have the time/ motivation to eat your veggies then carrot juice is a good way to achieve this effect, just do so sparingly and do your research on too much beta-carotene consumption. 2003;35(11):1815-1820. Jiang H, Yin Y, Wu CR, et al. Arterioscler Thromb Vasc Biol 1995;15:1057-63. Lee, J., Jiang, S., Levine, N., and Watson, R. R. Carotenoid supplementation reduces erythema in human skin after simulated solar radiation exposure. The effect of alpha-tocopherol and beta-carotene supplementation on COPD symptoms. Also, men who smoke and take beta-carotene supplements have in increased risk of developing prostate cancer. BY MOUTH: Did you or will you purchase this product in-store or online? Am J Clin Nutr 2004;79:1029-36. Build up of fat in the liver in people who drink little or no alcohol (nonalcoholic fatty liver disease or NAFLD). 38. A., and Pons, A. 12-6-1995;87(23):1760-1766. View abstract. View abstract. Bayerl, C., Schwarz, B., and Jung, E. G. A three-year randomized trial in patients with dysplastic naevi treated with oral beta-carotene. Arnlov, J., Zethelius, B., Riserus, U., Basu, S., Berne, C., Vessby, B., Alfthan, G., and Helmersson, J. Serum and dietary beta-carotene and alpha-tocopherol and incidence of type 2 diabetes mellitus in a community-based study of Swedish men: report from the Uppsala Longitudinal Study of Adult Men (ULSAM) study. 1999;33(1):16-17. It also doesn't seem to reduce the risk of colon tumor recurrence in people who have had colon tumors removed, although it might reduce the risk of colon tumor recurrence in people who never drink or smoke. View abstract. He J, Gu Y, Zhang S. Vitamin A and Breast Cancer Survival: A Systematic Review and Meta-analysis. 2000;223(2):170-174. Swelling (inflammation) and sores inside the mouth (oral mucositis). View abstract. View abstract. Available at: https://cot.food.gov.uk/sites/default/files/vitmin2003.pdf. View abstract. Also, taking beta-carotene might stop cancer-like lesions in the stomach from turning into cancer. Diet, tobacco use, and fatal prostate cancer: results from the Lutheran Brotherhood Cohort Study. Serum beta-carotene, retinol, and alpha-tocopherol levels during mineral oil therapy for constipation. J Natl Cancer Inst 2000;92:1881-8. Famously, a 1996 study on the effects of beta-carotene supplements on smokers was stopped after "excess lung cancer incidence and mortality" in participants. Beta Carotene Supplement Recommendations. View abstract. Ruiz, B., Garay, J., Correa, P., Fontham, E. T., Bravo, J. C., Bravo, L. E., Realpe, J. L., and Mera, R. Morphometric evaluation of gastric antral atrophy: improvement after cure of Helicobacter pylori infection. Am J Digestive Dis 1952;19:344-8. Frieling UM, Schaumberg DA, Kupper TS, et al. Ophthalmic Epidemiol. Neuroepidemiology. Am J Dis Child 1987;141:1210-2. van Leeuwen R, Boekhoorn S, Vingerling JR, et al. View abstract. View abstract. Oliveira-Menegozzo, J. M., Bergamaschi, D. P., Middleton, P., and East, C. E. Vitamin A supplementation for postpartum women. Bjelakovic, G., Nikolova, D., Simonetti, R. G., and Gluud, C. Systematic review: primary and secondary prevention of gastrointestinal cancers with antioxidant supplements. Coodley, G. O., Nelson, H. D., Loveless, M. O., and Folk, C. Beta-carotene in HIV infection. 2001;86(5):569-575. Dietary carotenoids and lung cancer: a review of recent research. Plummer, M., Vivas, J., Lopez, G., Bravo, J. C., Peraza, S., Carillo, E., Cano, E., Castro, D., Andrade, O., Sanchez, V., Garcia, R., Buiatti, E., Aebischer, C., Franceschi, S., Oliver, W., and Munoz, N. Chemoprevention of precancerous gastric lesions with antioxidant vitamin supplementation: a randomized trial in a high-risk population. View abstract. Colorectal Dis. 2011;118(11):1285-1291. CONCLUSIONS. Also, there is some evidence that taking beta-carotene supplements increases the risk of bleeding in the brain in people who drink alcohol. Fitzgerald KC, O'Reilly ÉJ, Fondell E, et al. Schuurman, A. G., Goldbohm, R. A., Brants, H. A., and van den Brandt, P. A. I can try and paraphrase, but honestly the article is pretty cogent and easy to read for a scientific paper. *NO DIAGNOSIS QUESTIONS. Ribeiro BD, Barreto DW, Coelho MAZ. While large amounts of supplemental vitamin A can be toxic, the human body will only convert as much beta carotene into vitamin A as it needs. They also contain Riboflavin for the maintenance of normal skin hailed as a ‘tan accelerating ingredient’, Selenium & Vitamin E to help protect the skin from oxaditive stress, Vitamin C, Copper citrate, Zinc citrate and L-tryosine. JAMA 1994;272:1413-20. Study ( United states ). of alpha-tocopherol and beta-carotene supplements does n't seem to reduce the prevalence precancerous. 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